HSV-1 is most often associated with orofacial (mouth, lips, tongue, pharynx, and eyes) transmission and infection, with 70 to 80% seropositivity in U.S. There are two well-recognized species of HSV classified as HSV type 1 (HSV-1) and HSV type 2 (HSV-2). Infection with HSV produces a variety of clinical manifestations, ranging from mild stomatitis to potentially fatal viral encephalitis. Herpes simplex virus (HSV) occurs worldwide and is one of the most common human pathogens. Advantages of the multiplex assay include multiple results per assay, the inclusion of internal controls for each specimen, and higher throughput of results. Our studies show that the multiplexed microsphere-based assay offers a sensitive and specific alternative method for the detection HSV-1 and -2 type-specific antibodies. For HSV-2, the sensitivity and specificity ranges were 92.6 to 98.9% and 98.3 to 98.7%, respectively. Sensitivities for HSV-1 ranged from 94.9 to 97.9%, with specificities of 93 to 97%. Agreement of the multiplex assay was 95% or greater ( n = 332) for both HSV-1 and -2 compared to the three assays. In this study, a multiplex assay capable of concurrent detection of HSV-1 and -2 immunoglobulin G (IgG) antibodies was compared to immunoblot, Western blot, and enzyme-linked immunosorbent assays. Differentiation of antibodies to these specific antigens can provide useful information for the diagnosis of subclinical or undiagnosed HSV-2 infections, as well as for reducing the risk of maternal transfer of HSV to the neonate. Let us know if this does not answer your question or if you have any additional questions or concerns.The human herpes simplex virus (HSV) is highly pathogenic, with infections caused by two distinct antigenic types, HSV-1 and HSV-2. I know it can be difficult to arrange sometimes, but if you do get similar symptoms again it would be good to get into the clinic while you are still experiencing symptoms as this can make it easier for the clinic to work out what is going on. If your hepatitis B blood test is negative for the hepatitis B virus and you have no protection against it I would recommend to get the vaccine straight away. If you’re unsure about your vaccination history in regard to hepatitis B, you can get a blood test for this to see if you have been vaccinated. Given this it’s possible to still be safer while waiting to see about your HSV result. If someone did have herpes the best advice we give them to avoid transmitting it to someone else is to not have sex when someone is having symptoms and to use a condom. The best test would be a swab from the area as that would let you know if it was herpes and if so what type. A common sign of herpes is that it is a reoccurring infection. I think the best thing would be to wait and see if the symptoms return in the next few months. If you do decide to do the herpes blood tests again I would talk with the health professional you see to discuss the pro/cons of the test. The herpes blood tests can be a bit tricky as it’s possible to get an inaccurate result (chance of a false positive or false negative result). We find that most people with HIV or syphilis would show it in a test by 6 weeks, but we recommend a final test at 3 months just to make sure.Ī herpes simplex virus (HSV) blood test (IgG) should detect something by 4 months. Gonorrhea and chlamydia would give you a final result by 6 weeks. You would expect most STI tests would give you a good result by 6 weeks.
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